I'm assuming you had Pico 5 setup for the 3000 under File/Setup/Converter.
Might substitute another USB cable just to be sure there is nothing wrong there. It's unusual but, at this point, I would be suspecting a hardware issue.
Is the scope identified as a PicoScope 3000 PC Based Oscilloscope in device manager? Has it worked on one of these PCs before? If so, when did it stop working? Was there an event associated with the failure?
I'm sure one of the Pico staff will be able to help you further with instructions for getting that taken care of.
THE PicoScope Automotive Authority
In North America